South America

South America Cruises

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Recommended Sailings

SOUTH AMERICA CRUISES

  • MSC Poesia
    3.1 rating out of 5  (248 reviews)

    9 Night South America

    MSC Poesia

    Departing from: Buenos Aires, Argentina
    Ports of Call:
    • Montevideo, Uruguay
    • Camboriu, Brazil
    • Ilhabela, Brazil
    • Buzios, Brazil
    • Rio De Janeiro, Brazil
    Sailing Dates:
    • January 2025
    • February 2025
    interior from
    Call for availability
    oceanview from
    Call for availability
    balcony from
    $1,806
    $201pernight
    suite from
    $2,696
    $300pernight
    All the Cruise Line Offers & More:
    • AAdvantage® Members: 1 Mile Per $1
    • AAdvantage® Credit Cardmembers get even more miles
    • Escape to Sea Sale!
    • The MSC Cruise Experience: Click to Learn More
     
    Balcony from $1,806
    ($201pernight)
    3.1 rating out of 5  (248 reviews)
  • MSC Poesia
    3.1 rating out of 5  (248 reviews)

    9 Night South America

    MSC Poesia

    Departing from: Buenos Aires, Argentina
    Ports of Call:
    • Montevideo, Uruguay
    • Porto Belo, Brazil
    • Ilhabela, Brazil
    • Buzios, Brazil
    • Rio De Janeiro, Brazil
    Sailing Dates:
    • March 2025
    interior from
    Call for availability
    oceanview from
    Call for availability
    balcony from
    $1,901
    $211pernight
    suite from
    $2,721
    $302pernight
    All the Cruise Line Offers & More:
    • AAdvantage® Members: 1 Mile Per $1
    • AAdvantage® Credit Cardmembers get even more miles
    • Escape to Sea Sale!
    • The MSC Cruise Experience: Click to Learn More
     
    Balcony from $1,901
    ($211pernight)
    3.1 rating out of 5  (248 reviews)
  • Sapphire Princess
    4 rating out of 5  (565 reviews)

    18 Night Brazilian Adventure

    Sapphire Princess

    Departing from: Ft. Lauderdale (Port Everglades), Florida
    Ports of Call:
    • Basseterre, St. Kitts
    • Fortaleza, Brazil
    • Rio De Janeiro, Brazil
    • Montevideo, Uruguay
    • Buenos Aires, Argentina
    Sailing Dates:
    • November 2024
    interior from
    $1,279
    $71pernight
    oceanview from
    $1,398
    $78pernight
    balcony from
    $1,729
    $96pernight
    suite from
    $2,229
    $124pernight
    All the Cruise Line Offers & More:
    • Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
    • AAdvantage® Members: 1 Mile Per $1
    • AAdvantage® Credit Cardmembers get even more miles
    • Drop & Go Sale: Limited Time Reduced Rates!
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Here Comes the Sun Sale: Save up to 40%
     
    Interior from $1,279
    ($71pernight)
    4 rating out of 5  (565 reviews)
  • Sapphire Princess
    4 rating out of 5  (565 reviews)

    18 Night Andes & South America

    Sapphire Princess

    Departing from: San Antonio (Santiago), Chile
    Ports of Call:
    • Coquimbo (La Serena), Chile
    • General San Martin (Pisco), Peru
    • Callao (Lima), Peru
    • Manta, Ecuador
    • Puntarenas, Costa Rica
    • Puerto Vallarta, Mexico
    • Cabo San Lucas, Mexico
    • San Pedro (Los Angeles), California
    Sailing Dates:
    • March 2025
    interior from
    $1,639
    $91pernight
    oceanview from
    $1,753
    $97pernight
    balcony from
    $2,489
    $138pernight
    suite from
    $3,089
    $172pernight
    All the Cruise Line Offers & More:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
    • AAdvantage® Members: 1 Mile Per $1
    • AAdvantage® Credit Cardmembers get even more miles
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Here Comes the Sun Sale: Save up to 40%
     
    Interior from $1,639
    ($91pernight)
    4 rating out of 5  (565 reviews)
  • Majestic Princess
    4.4 rating out of 5  (407 reviews)

    18 Night Brazilian Adventure

    Majestic Princess

    Departing from: Buenos Aires, Argentina
    Ports of Call:
    • Montevideo, Uruguay
    • Rio De Janeiro, Brazil
    • Fortaleza, Brazil
    • Dominica
    • Basseterre, St. Kitts
    • Ft. Lauderdale (Port Everglades), Florida
    Sailing Dates:
    • January 2025
    interior from
    $1,899
    $106pernight
    oceanview from
    Not Available
    balcony from
    $1,662
    $92pernight
    suite from
    $2,289
    $127pernight
    All the Cruise Line Offers & More:
    • Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
    • AAdvantage® Members: 1 Mile Per $1
    • AAdvantage® Credit Cardmembers get even more miles
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Here Comes the Sun Sale: Save up to 40%
     
    Balcony from $1,662
    ($92pernight)
    4.4 rating out of 5  (407 reviews)
  • Majestic Princess
    4.4 rating out of 5  (407 reviews)

    18 Night Andes & South America

    Majestic Princess

    Departing from: San Pedro (Los Angeles), California
    Ports of Call:
    • Puerto Vallarta, Mexico
    • Panama City (Fuerte Amador), Panama
    • Callao (Lima), Peru
    • Pisco (Nazca Lines), Peru
    • Coquimbo (La Serena), Chile
    • San Antonio (Santiago), Chile
    Sailing Dates:
    • December 2024
    interior from
    $1,578
    $88pernight
    oceanview from
    Not Available
    balcony from
    $1,878
    $104pernight
    suite from
    $2,378
    $132pernight
    All the Cruise Line Offers & More:
    • Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
    • AAdvantage® Members: 1 Mile Per $1
    • AAdvantage® Credit Cardmembers get even more miles
    • Drop & Go Sale: Limited Time Reduced Rates!
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Here Comes the Sun Sale: Save up to 40%
     
    Interior from $1,578
    ($88pernight)
    4.4 rating out of 5  (407 reviews)
  • Norwegian Star
    3.6 rating out of 5  (2,045 reviews)

    16 Night Transatlantic: Brazil & Canary Islands

    Norwegian Star - OPEN BAR!

    Departing from: Rio De Janeiro, Brazil
    Ports of Call:
    • Buzios, Brazil
    • Salvador De Bahia, Brazil
    • Maceio, Brazil
    • Recife, Brazil
    • Porto Grande, Cape Verde Islands
    • Santa Maria, Azores, Portugal
    • Santa Cruz De Tenerife, Canary Islands
    • Las Palmas, Gran Canaria, Canary Islands
    • Funchal, Madeira, Portugal
    • Lisbon, Portugal
    Sailing Dates:
    • March 2025
    interior from
    $1,522
    $95pernight
    oceanview from
    $1,722
    $108pernight
    balcony from
    $2,762
    $173pernight
    suite from
    $3,252
    $203pernight
    All the Cruise Line Offers & More:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Exclusive: Up to $400 to Spend on Board
    • Save up to $150 Instantly! Call and Mention: CruiseFirst
    • AAdvantage® Members: 1 Mile Per $1
    • AAdvantage® Credit Cardmembers get even more miles
    • 70% off 2nd Guest + Free at Sea Perks
     
    Interior from $1,522
    ($95pernight)
    3.6 rating out of 5  (2,045 reviews)
  • Sapphire Princess
    4 rating out of 5  (565 reviews)

    14 Night Cape Horn & Strait of Magellan

    Sapphire Princess

    Departing from: San Antonio (Santiago), Chile
    Ports of Call:
    • Puerto Montt, Chile
    • Cruise Amalia Glacier
    • Punta Arenas, Chile
    • Ushuaia, Tierra Del Fuego, Argentina
    • Cruise Cape Horn
    • Port Stanley, Falkland Islands
    • Puerto Madryn, Argentina
    • Montevideo, Uruguay
    • Buenos Aires, Argentina
    Sailing Dates:
    • February 2025
    interior from
    $2,619
    $187pernight
    oceanview from
    $2,733
    $195pernight
    balcony from
    $4,469
    $319pernight
    suite from
    $4,669
    $334pernight
    All the Cruise Line Offers & More:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
    • AAdvantage® Members: 1 Mile Per $1
    • AAdvantage® Credit Cardmembers get even more miles
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Here Comes the Sun Sale: Save up to 40%
     
    Interior from $2,619
    ($187pernight)
    4 rating out of 5  (565 reviews)
  • Oosterdam
    4.1 rating out of 5  (885 reviews)

    14 Night South America Passage

    Oosterdam

    Departing from: San Antonio (Santiago), Chile
    Ports of Call:
    • Puerto Montt, Chile
    • Puerto Chacabuco, Chile
    • Cruise Chilean Fjords
    • Scenic Cruising Sarmiento Channel
    • Cruise Strait Of Magellan
    • Punta Arenas, Chile
    • Cruise Cockburn & Beagle Channels
    • Cruise Glacier Alley
    • Ushuaia, Tierra Del Fuego, Argentina
    • Cruise Cape Horn
    • Port Stanley, Falkland Islands
    • Montevideo, Uruguay
    • Buenos Aires, Argentina
    Sailing Dates:
    • February 2025
    • December 2025
    • February 2026
    interior from
    $1,909
    $136pernight
    oceanview from
    $2,109
    $151pernight
    balcony from
    $3,174
    $227pernight
    suite from
    $4,194
    $300pernight
    All the Cruise Line Offers & More:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • AAdvantage® Members: 1 Mile Per $1
    • AAdvantage® Credit Cardmembers get even more miles
    • Free Drinks, Dining, and Excursions with Select Fares
    • Exclusive: Up to $150 to Spend on Board - Call
     
    Interior from $1,909
    ($136pernight)
    4.1 rating out of 5  (885 reviews)
  • Celebrity Equinox
    4.3 rating out of 5  (1,909 reviews)

    14 Night Patagonia & Argentina

    Celebrity Equinox

    Departing from: Buenos Aires, Argentina
    Ports of Call:
    • Montevideo, Uruguay
    • Port Stanley, Falkland Islands
    • Cruise Cape Horn
    • Ushuaia, Tierra Del Fuego, Argentina
    • Cruise Strait Of Magellan
    • Punta Arenas, Chile
    • Puerto Madryn, Argentina
    • Punta Del Este, Uruguay
    Sailing Dates:
    • December 2025
    • February 2026
    interior from
    $2,278
    $163pernight
    oceanview from
    $2,269
    $162pernight
    balcony from
    $2,844
    $203pernight
    suite from
    $6,502
    $464pernight
    All the Cruise Line Offers & More:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • AAdvantage® Members: 1 Mile Per $1
    • AAdvantage® Credit Cardmembers get even more miles
    • All-Included: Free Drinks & Wi-Fi
    • Flash Sale: 75% Off 2nd Guests & Up to $200 in Savings!
     
    Oceanview from $2,269
    ($162pernight)
    4.3 rating out of 5  (1,909 reviews)
  • Sapphire Princess
    4 rating out of 5  (565 reviews)

    14 Night Cape Horn & Strait of Magellan

    Sapphire Princess

    Departing from: Buenos Aires, Argentina
    Ports of Call:
    • Montevideo, Uruguay
    • Puerto Madryn, Argentina
    • Port Stanley, Falkland Islands
    • Cruise Cape Horn
    • Ushuaia, Tierra Del Fuego, Argentina
    • Punta Arenas, Chile
    • Cruise Amalia Glacier
    • Puerto Montt, Chile
    • San Antonio (Santiago), Chile
    Sailing Dates:
    • February 2025
    • March 2025
    interior from
    $2,378
    $170pernight
    oceanview from
    $2,485
    $178pernight
    balcony from
    $4,309
    $308pernight
    suite from
    $5,014
    $358pernight
    All the Cruise Line Offers & More:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
    • AAdvantage® Members: 1 Mile Per $1
    • AAdvantage® Credit Cardmembers get even more miles
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Here Comes the Sun Sale: Save up to 40%
     
    Interior from $2,378
    ($170pernight)
    4 rating out of 5  (565 reviews)
  • Oosterdam
    4.1 rating out of 5  (885 reviews)

    14 Night South America Passage

    Oosterdam

    Departing from: Buenos Aires, Argentina
    Ports of Call:
    • Montevideo, Uruguay
    • Port Stanley, Falkland Islands
    • Cruise Cape Horn
    • Ushuaia, Tierra Del Fuego, Argentina
    • Cruise Beagle Channel
    • Cruise Glacier Alley
    • Cruise Strait Of Magellan
    • Punta Arenas, Chile
    • Cruise Cockburn Channel
    • Cruise Strait Of Magellan
    • Puerto Montt, Chile
    • San Antonio (Santiago), Chile
    Sailing Dates:
    • March 2025
    • March 2026
    interior from
    $1,969
    $141pernight
    oceanview from
    $2,119
    $151pernight
    balcony from
    $3,454
    $247pernight
    suite from
    $3,919
    $280pernight
    All the Cruise Line Offers & More:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • AAdvantage® Members: 1 Mile Per $1
    • AAdvantage® Credit Cardmembers get even more miles
    • Free Drinks, Dining, and Excursions with Select Fares
    • Exclusive: Up to $150 to Spend on Board - Call
     
    Interior from $1,969
    ($141pernight)
    4.1 rating out of 5  (885 reviews)
  • Norwegian Jade
    3.9 rating out of 5  (1,389 reviews)

    17 Night South America: Cabo & Trujillo

    Norwegian Jade - OPEN BAR!

    Departing from: Callao (Lima), Peru
    Ports of Call:
    • Salaverry (Trujillo), Peru
    • Manta, Ecuador
    • Panama City, Panama
    • Puntarenas, Costa Rica
    • San Juan Del Sur, Nicaragua
    • Acajutla, El Salvador
    • Puerto Quetzal, Guatemala
    • Huatulco, Mexico
    • Acapulco, Mexico
    • Manzanillo, Mexico
    • Puerto Vallarta, Mexico
    • Cabo San Lucas, Mexico
    • San Diego, California
    Sailing Dates:
    • March 2026
    interior from
    $2,089
    $123pernight
    oceanview from
    $2,599
    $153pernight
    balcony from
    $4,049
    $238pernight
    suite from
    $4,830
    $284pernight
    All the Cruise Line Offers & More:
    • Exclusive: Up to $400 to Spend on Board
    • Save up to $150 Instantly! Call and Mention: CruiseFirst
    • 70% off 2nd Guest + Free at Sea Perks
     
    Interior from $2,089
    ($123pernight)
    3.9 rating out of 5  (1,389 reviews)
  • Celebrity Equinox
    4.3 rating out of 5  (1,909 reviews)

    14 Night Patagonia & Argentina Holiday

    Celebrity Equinox

    Departing from: Buenos Aires, Argentina
    Ports of Call:
    • Montevideo, Uruguay
    • Port Stanley, Falkland Islands
    • Cruise Cape Horn
    • Ushuaia, Tierra Del Fuego, Argentina
    • Cruise Strait Of Magellan
    • Punta Arenas, Chile
    • Puerto Madryn, Argentina
    • Punta Del Este, Uruguay
    Sailing Dates:
    • December 2025
    interior from
    $2,455
    $175pernight
    oceanview from
    $2,637
    $188pernight
    balcony from
    $3,287
    $235pernight
    suite from
    $7,885
    $563pernight
    All the Cruise Line Offers & More:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • AAdvantage® Members: 1 Mile Per $1
    • AAdvantage® Credit Cardmembers get even more miles
    • All-Included: Free Drinks & Wi-Fi
    • Flash Sale: 75% Off 2nd Guests & Up to $200 in Savings!
     
    Interior from $2,455
    ($175pernight)
    4.3 rating out of 5  (1,909 reviews)
  • Majestic Princess
    4.4 rating out of 5  (407 reviews)

    15 Night Cape Horn & Strait of Magellan

    Majestic Princess

    Departing from: San Antonio (Santiago), Chile
    Ports of Call:
    • Puerto Montt, Chile
    • Cruise Amalia Glacier
    • Punta Arenas, Chile
    • Ushuaia, Tierra Del Fuego, Argentina
    • Cruise Cape Horn
    • Port Stanley, Falkland Islands
    • Puerto Madryn, Argentina
    • Montevideo, Uruguay
    • Buenos Aires, Argentina
    Sailing Dates:
    • December 2024
    interior from
    $3,073
    $205pernight
    oceanview from
    Not Available
    balcony from
    $3,036
    $202pernight
    suite from
    $3,979
    $265pernight
    All the Cruise Line Offers & More:
    • Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
    • AAdvantage® Members: 1 Mile Per $1
    • AAdvantage® Credit Cardmembers get even more miles
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Here Comes the Sun Sale: Save up to 40%
     
    Balcony from $3,036
    ($202pernight)
    4.4 rating out of 5  (407 reviews)
  • Azamara Journey
    4.3 rating out of 5  (137 reviews)

    10 Night Peru & Chile Voyage

    Azamara Journey

    Departing from: Callao (Lima), Peru
    Ports of Call:
    • Pisco (Nazca Lines), Peru
    • Arica, Chile
    • Iquique, Chile
    • Antofagasta, Chile
    • Coquimbo (La Serena), Chile
    • San Antonio (Santiago), Chile
    Sailing Dates:
    • January 2025
    interior from
    $2,119
    $212pernight
    oceanview from
    $2,159
    $216pernight
    balcony from
    $2,869
    $287pernight
    suite from
    $5,929
    $593pernight
    All the Cruise Line Offers & More:
    • Up to $500 to Spend on Board
    • Choose: Complimentary Beverage Package or Unlimited Wi-Fi
    • Free Gratuities, Select Beverages, Exclusive Cultural Events, and More
    • AAdvantage® Members: 1 Mile Per $1
    • AAdvantage® Credit Cardmembers get even more miles
     
    Interior from $2,119
    ($212pernight)
    4.3 rating out of 5  (137 reviews)
  • Viking Sea
    4.4 rating out of 5  (83 reviews)

    12 Night Amazon & Caribbean Adventure

    Viking Sea

    Departing from: Manaus (Amazon River), Brazil
    Ports of Call:
    • Parintins (Amazon River), Brazil
    • Santarem (Amazon River), Brazil
    • Cruise Amazon River
    • Devils Island, French Guiana
    • Bridgetown, Barbados
    • Castries, St. Lucia
    • Basseterre, St. Kitts
    • San Juan, Puerto Rico
    Sailing Dates:
    • December 2024
    • January 2025
    • March 2025
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $4,299
    $358pernight
    suite from
    $7,999
    $667pernight
    All the Cruise Line Offers & More:
    • Limited Time: $25 Deposits
    • AAdvantage® Members: 1 Mile Per $1
    • AAdvantage® Credit Cardmembers get even more miles
    • Includes Abundant Dining Options, Wi-Fi, more
    • Call for the Best Value
     
    Balcony from $4,299
    ($358pernight)
    4.4 rating out of 5  (83 reviews)
  • Viking Sea
    4.4 rating out of 5  (83 reviews)

    12 Night Amazon & Caribbean Adventure

    Viking Sea

    Departing from: San Juan, Puerto Rico
    Ports of Call:
    • St. Johns, Antigua
    • Castries, St. Lucia
    • Bridgetown, Barbados
    • Devils Island, French Guiana
    • Cruise Amazon River
    • Santarem (Amazon River), Brazil
    • Parintins (Amazon River), Brazil
    • Manaus (Amazon River), Brazil
    Sailing Dates:
    • November 2024
    • January 2025
    • February 2025
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $4,299
    $358pernight
    suite from
    $7,599
    $633pernight
    All the Cruise Line Offers & More:
    • Limited Time: $25 Deposits
    • AAdvantage® Members: 1 Mile Per $1
    • AAdvantage® Credit Cardmembers get even more miles
    • Includes Abundant Dining Options, Wi-Fi, more
    • Call for the Best Value
     
    Balcony from $4,299
    ($358pernight)
    4.4 rating out of 5  (83 reviews)

Experience the Thrill of a South America Cruise

Get the Best Deals on a South America Cruise

Take pleasure in a cruise adventure of a lifetime when you travel to South America with American Airlines Cruises.

Your sailing will begin from the always chic and star-studded city of Miami, FL. Enjoy South Florida’s most famed district by soaking up the sun on South Beach, dine in a beachside restaurant or relax at an outdoor café.

Aboard a grand ship, you’ll set sail for places like Cartagena, a city known for its exterior beauty resting on the northern coast of Columbia in the Caribbean Coast Region. Colon, Panama is a popular cruise destination, and one you won’t want to miss. Its main attraction, arguably, is the infamous Panama Canal, one of the world’s greatest engineering feats made by man.

To the east, your South America cruise itineraries include ports like Santos (Sao Paulo), Brazil, where the soft sands of the beaches connect with the crystal blue waters of the Atlantic. In Buenos Aires, visit Plaza Intendente Alvear, an event livened area littered with street performers, colorful crafts and souvenir markets. Lose yourself in the street fairs of Montevideo, Uruguay and indulge in a local dish, or shop till you drop in one of many specialty boutiques.

A South America cruise with American Airlines Cruises offers a wide-range of diverse pleasure-seeking activities such as shopping, exceptional sightseeing, beach fun, new dining experiences and more.

South America Cruises


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